If you are looking for a comfort food that feels indulgent yet easy enough to whip up anytime, this Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is an absolute winner. Picture tender, Cajun-spiced chicken mingling with perfectly cooked spaghetti all wrapped in a creamy, garlicky mozzarella sauce that feels like a warm hug on a plate. Each bite bursts with flavor—the subtle heat from the Cajun seasoning balanced by the gooey mozzarella and the aromatic garlic. This dish is perfect for busy weeknights or when you want to impress without fuss.

n Spaghetti with Garlic Mozzarella Sauce Recipe - Recipe Image

Ingredients You’ll Need

The magic of Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce lies in its simple yet thoughtfully chosen ingredients. Each component plays a vital role, from enriching the sauce’s creaminess to bringing that irresistible Cajun kick to the chicken. Having these staples ready means this dish comes together quickly without compromising on flavor.

1 pound boneless, skinless chicken breasts: Provides tender, protein-packed bites with a mild flavor perfect for seasoning.

2 tablespoons olive oil: Helps brown the chicken for a crispy, flavorful exterior.
2 tablespoons Cajun seasoning: Adds that signature spicy, smoky flavor that wakes up the palate.

1 teaspoon smoked paprika: Brings depth and a subtle smoky undertone to the chicken.
1 pound spaghetti: The classic pasta base; cooks al dente to perfectly hold the thick sauce.

4 tablespoons butter: Essential for making the rich garlic roux foundation of the sauce.
4 cloves garlic, minced: Infuses the sauce with bright, aromatic notes that marry beautifully with mozzarella.
1/4 cup all-purpose flour: Thickens the sauce to a luscious, creamy consistency.

3 cups whole milk: Creates the creamy base, balancing richness and silkiness.
1 cup chicken broth: Adds savory depth and helps loosen the sauce.
8 ounces cream cheese, softened: Boosts creaminess and smooth texture in the sauce.

2 cups shredded mozzarella cheese, divided: Gives that irresistibly stretchy, melty cheese pull in the sauce and on top.
1/2 cup grated Parmesan cheese: Adds umami and a slightly nutty finish to the sauce.
Salt and freshly ground black pepper: To taste—essential seasoning to enhance all the flavors.

Optional: Red pepper flakes: For anyone wanting to dial up the heat a bit.

How to Make Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Step 1: Cook the Spaghetti

Start by bringing a large pot of salted water to a boil and cook the spaghetti following the package instructions until al dente. Properly cooked pasta is the foundation here—it should be tender but still have a slight bite so it holds up under the creamy sauce. Once done, drain and set aside but keep it warm for tossing later.

Step 2: Season and Cook the Chicken

While the pasta cooks, season your bite-sized chicken pieces with Cajun seasoning and smoked paprika. These spices work together to create that signature flavor that makes this dish pop. Heat olive oil in a large skillet over medium-high heat, then add the chicken. Cook until browned and cooked through, about 6 to 8 minutes. Removing the chicken once done keeps it juicy and lets you build the sauce in the same skillet, maximizing flavor.

Step 3: Make the Garlic Mozzarella Sauce

Using the skillet where the chicken cooked, melt butter over medium heat. Add the minced garlic and sauté it just until fragrant—don’t let it burn, as garlic sets the tone for the entire sauce. Next, sprinkle in the flour and whisk constantly for one to two minutes to create a roux, which is key for thickening the sauce. Slowly whisk in the milk and chicken broth, stirring constantly to avoid lumps, until everything blends into a smooth liquid. Bring this mixture to a gentle simmer to develop that perfect creamy texture.

Step 4: Add Cheeses and Finish the Sauce

Once simmering, stir in the cream cheese and one cup of mozzarella until melted and completely smooth. Then add the Parmesan cheese and season with salt, freshly ground black pepper, and red pepper flakes if you like a little extra kick. Return the cooked chicken to the skillet and let it simmer in the sauce for 2 to 3 minutes to soak up all those wonderful flavors before adding the pasta.

Step 5: Combine Pasta and Sauce

Add the cooked spaghetti to the skillet and toss gently to coat every strand in that dreamy garlic mozzarella sauce. To really drive home that melty, cheesy goodness, sprinkle the remaining mozzarella over the top, cover the pan, and let it sit for a few minutes just long enough for the cheese to melt beautifully. You’ll be greeted by a bubbling, cheesy masterpiece ready to serve.

How to Serve Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Garnishes

A sprinkle of freshly chopped parsley not only brightens the dish visually but also adds a fresh herbal note that cuts through the richness. Additional grated Parmesan on top elevates the umami factor, making each bite richer and more satisfying. For a little sparkle, a dash of red pepper flakes can add color and a gentle heat for those who love a bit of spice.

Side Dishes

Since Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is a hearty main, it pairs beautifully with simple, crisp sides like a fresh green salad with a tangy vinaigrette to balance the creamy sauce. Garlic bread or a warm baguette is perfect for mopping up any leftover sauce—because trust me, you won’t want to waste a single drop! Roasted or steamed seasonal vegetables also complement this dish nicely, adding color and texture contrast.

Creative Ways to Present

For a dinner party, serve the spaghetti in shallow bowls with a sprinkle of fresh herbs and a small wedge of lemon on the side to add a citrusy brightness. Alternatively, create individual casseroles by layering the pasta, chicken, and sauce in small ramekins topped with mozzarella, then baking until golden and bubbly. This presentation gives a homey yet elegant touch that guests will adore.

Make Ahead and Storage

Storing Leftovers

Leftover Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce tastes fantastic the next day once the flavors have melded even further. Store in an airtight container in the refrigerator for up to 3 days. Make sure to cool the dish completely before sealing to keep it fresh and safe.

Freezing

This dish can be frozen, but be mindful that the texture of the creamy sauce might change slightly when thawed. For best results, freeze in a heavy-duty freezer container for up to 2 months. Thaw overnight in the fridge before reheating.

Reheating

When ready to enjoy leftovers, reheat gently on the stove over low to medium heat, stirring frequently to prevent the sauce from separating. Adding a splash of milk or chicken broth can revive the sauce’s creaminess. Microwaving works too, but stirring halfway through helps maintain an even temperature.

FAQs

Can I use different pasta for this recipe?

Absolutely! While spaghetti is traditional and works beautifully to hold the sauce, feel free to swap in fettuccine, penne, or even rotini to change up the texture or fit what you have on hand.

Is this dish very spicy?

The level of heat comes mainly from the Cajun seasoning and the optional red pepper flakes. You can easily adjust the spice by reducing these or omitting the flakes if you prefer a milder flavor. It’s easily customizable to your taste buds.

Can I make this recipe dairy-free?

This version relies heavily on dairy for creaminess, but you can experiment with dairy-free cream cheese, plant-based milk, and vegan mozzarella alternatives. The flavor profile will be different but can still be delicious with some adjustments.

What’s the best way to ensure the chicken stays juicy?

Cutting chicken into bite-sized pieces and cooking it just until browned and cooked through prevents dryness. Cooking over medium-high heat for 6–8 minutes ensures it’s sealed and tender inside.

Can I prepare the sauce ahead of time?

You can make the garlic mozzarella sauce a few hours ahead and keep it warm, but it’s best to combine with freshly cooked spaghetti and chicken just before serving to keep the sauce silky and the pasta perfectly textured.

Final Thoughts

I cannot recommend this Easy Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce enough for anyone craving a creamy, flavorful dinner that brings a smile with every bite. It’s simple enough for weekday meals but special enough to make any dinner feel like a celebration. So grab those ingredients, get cooking, and let this dish become your new go-to comfort food you’ll want to share again and again!